10 Natural Remedies to Relieve Allergies

 Exercise

Nasal Irrigation

Vitamin D

Acupuncture

Butterbur

Quercetin

Omega-3 Fatty Acids

Stinging Nettle

Probiotics and Prebiotics

Black Cumin Seed Oil

Exercise

Regular exercise may be one of the most effective ways to help decrease allergic reactions, including respiratory allergies (related to breathing), although it isn't quite clear why. In moderation, exercise isn't harmful to people who have allergies and, of course, offers many health benefits.

Nasal Irrigation

Nasal irrigation, also called nasal rinse or saline lavage, is often used by people who have allergies with respiratory symptoms. It is an at-home remedy that involves using sterile saltwater to clear nasal passages.

Vitamin D

Vitamin D deficiency has been linked to allergies, including allergic rhinitis (nasal congestion), allergic asthma, eczema, and anaphylaxis.5 This vitamin has a role in regulating immune system cells and the release of chemicals that can produce allergy symptoms.

Acupuncture

The American Academy of Otolaryngology-Head and Neck Surgery Foundation recommends acupuncture as one way to treat allergic rhinitis.

Acupuncture Is Used

Acupuncture is often used as a complementary therapy in addition to conventional allergy treatment. In visiting an acupuncturist, you would get a series of weekly or twice-weekly treatments for several weeks, and then follow-up treatments as needed.

Butterbur

The herb butterbur (Petasites hybridus) is a shrub-like plant that grows in northern Asia, Europe, and parts of North America. Extracts from the herb have been used in folk medicine for migraine headaches, stomach cramps, cough, allergic rhinitis, and asthma.12

Quercetin

Quercetin is an antioxidant, which helps prevent damage to cells. It reduces inflammatory cells and proteins, especially in skin.14 It is found naturally in foods such as apples (with the skin on), berries, red grapes, red onions, capers, and black tea. It is also available in supplement form.

Some people use it for allergic rhinitis, atopic dermatitis (eczema), and asthma.

Omega-3 Fatty Acids

Omega-3 fatty acids are essential fats. These are fats your body needs but can't make itself, so you need to get them from your diet. Foods that are rich in omega-3 fatty acids include fish, walnuts, vegetable oil, flax seeds, and leafy vegetables.

Research suggests that omega-3 fatty acids may reduce the production of inflammatory chemicals in the body, which have a role in allergies and asthma.17

Stinging Nettle

Stinging nettle (Urtica dioica) is an herb that may reduce the symptoms of allergic rhinitis. This natural remedy is thought by some to be one of the most effective herbal supplements for relieving allergy symptoms.

Probiotics and Prebiotics

Probiotics are live organisms, or "good" bacteria, that help improve the health of the digestive and immune systems.

Prebiotics are a type of fiber that encourages the growth of probiotic bacteria. Added to infant formula, they may help improve immune responses.

Black Cumin Seed Oil

Black cumin seed oil has several active chemical compounds, including thymoquinone, which evidence suggests may relieve symptoms of allergic rhinitis.

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How to recognise early signs and symptoms of skin cancer

 How to recognise early signs and symptoms of skin cancer

Some forms of skin cancers develop where they are visible to the naked eye. Therefore, there is a good chance one can notice them early before it becomes fatal.

One way to recognise skin cancer early is to keep an eye for any new or unusual growths on the skin or changes in existing moles. If you notice anything unusual or suspicious then you should immediately consult your physician or a dermatologist (skin doctor).An unusual skin growth or sore that refuses to heal may be the first indication of a non-melanoma skin cancer. According to health experts skin cancer may initially appear as a nodule, rash or irregular patch on the surface of the skin, adding that these spots may be raised and may ooze or bleed easily.

As the cancer grows, the size or shape of the visible skin mass may change and the cancer may grow into deeper layers of the skin. It may be difficult to differentiate one form of skin cancer from another, therefore, it is best to consult a dermatologist.

Explaining these unusual growths on the skin experts say that “Basal cell carcinomas on the head or neck may first appear as a pale patch of skin or a waxy translucent bump. You may see blood vessels or an indentation in the center of the bump. If the carcinoma develops on the chest, it may look more like a brownish scar or flesh-colored lesion. As the cancer develops, it may bleed if injured or ooze and become crusty in some areas”.

Squamous cell carcinomas may also develop as a lump on the skin. These firm lumps are typically rough on the surface, unlike the smooth and pearly appearance of a basal cell carcinoma. If a nodule doesn't form, the cancer may develop more like a reddish, scaly patch. Unlike a skin rash that goes away with time, these rough, lesion-like patches continue to develop slowly. This type of cancer is typically found on the head, neck, hands or arms, but they may also develop in other areas, such as the genital region or in scars or skin sores.

Merkel cell carcinomas may appear as red or flesh-colored moles that are raised and grow quickly. These small tumors usually appear on that part of the skin that is exposed to the sun, like the face, neck or scalp.

Skin cancer can develop in body parts which are not normally exposed to the sun also. Therefore, in addition to examining the legs, trunk, arms, face and neck, it is important to look for signs of skin cancer in the areas between the toes, underneath nails, palms of the hands and soles of the feet, genitals and even the eyes.

Skin cancer is not specific to any particular type of skin and it affects people of all skin tones, including those with darker complexions. When melanoma occurs in people with dark skin tones, it's more likely to occur in areas not normally exposed to the sun, such as the palms of the hands and soles of the feet.

The most common types of skin cancer are:

Basal cell carcinoma

Basal cell carcinoma usually occurs in those body parts which are exposed to the sun, such as your neck or face.

Basal cell carcinoma may appear as:

A pearly or waxy bump

A flat, flesh-colored or brown scar-like lesion

A bleeding or scabbing sore that heals and returns

Squamous cell carcinoma

Most often, squamous cell carcinoma occurs on sun-exposed areas of your body, such as your face, ears and hands. This appears more likely on people with darker skin and more likely to develop squamous cell carcinoma on areas that aren't often exposed to the sun.

Squamous cell carcinoma may appear as:

A firm, red nodule

A flat lesion with a scaly, crusted surface

Melanoma

Melanoma can develop anywhere on your body, in otherwise normal skin or in an existing mole and becomes cancerous. Melanoma most often appears on the face or the trunk of affected men. In women, this type of cancer mostly develops on the lower legs. In both men and women, melanoma can occur on skin that hasn't been exposed to the sun.

Melanoma can also affect people of any skin tone. People with darker skin tones, melanoma tends to occur on the palms or soles, or under the fingernails or toenails.

Melanoma symptoms include:

A large brownish spot with darker speckles

A mole that changes in color, size or feel or that bleeds

A small lesion with an irregular border and portions that appear red, pink, white, blue or blue-black

A painful lesion that itches or burns

Dark lesions on your palms, soles, fingertips or toes, or on mucous membranes lining your mouth, nose, vagina or anus

Signs and symptoms of less common forms of skin cancers

Kaposi sarcoma. This rare form of skin cancer develops in the skin's blood vessels and causes red or purple patches on the skin or mucous membranes. Kaposi sarcoma mainly occurs in people who have a weakened immune system, such as people with AIDS, and in people taking medications that suppress their natural immunity, such as people who've undergone organ transplants. Other people with an increased risk of Kaposi sarcoma include young men living in Africa or older men of Italian or Eastern European Jewish heritage.

Merkel cell carcinoma. Merkel cell carcinoma causes firm, shiny nodules that occur on or just beneath the skin and in hair follicles. Merkel cell carcinoma is most often found on the head, neck and the trunk.

Sebaceous gland carcinoma. This uncommon and aggressive cancer originates in the oil glands in the skin. Sebaceous gland carcinomas — which usually appear as hard, painless nodules — can develop anywhere, but mostly occurs on the eyelid, where they're frequently mistaken for other eyelid problems.

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Rosacea

 Rosacea (roe-ZAY-she-uh) is a common skin condition that causes blushing or flushing and visible blood vessels in your face. It may also produce small, pus-filled bumps. These signs and symptoms may flare up for weeks to months and then go away for a while. Rosacea can be mistaken for acne, other skin problems or natural ruddiness.

Rosacea can affect anyone. But it's most common in middle-aged white women. There's no cure for rosacea, but treatment can control and reduce the signs and symptoms.

Symptoms

RhinophymaEnlarge image

Signs and symptoms of rosacea include:

• Facial blushing or flushing. Rosacea can cause a persistent blushing or flushing in the central part of your face. This sign of the condition may be difficult to see on brown and Black skin.

• Visible veins. Small blood vessels of your nose and cheeks break and become visible (spider veins).

• Swollen bumps. Many people with rosacea also develop pimples on their face that resemble acne. These bumps sometimes contain pus.

• Burning sensation. The skin of the affected area may feel hot and tender.

• Eye problems. Many people with rosacea also experience dry, irritated, swollen eyes and eyelids. This is known as ocular rosacea. In some people, the eye symptoms precede the skin symptoms.

• Enlarged nose. Over time, rosacea can thicken the skin on the nose, causing the nose to appear bulbous (rhinophyma). This occurs more often in men than in women.

When to see a doctor

If you experience persistent symptoms of your face or eyes, see your doctor or a skin specialist (dermatologist) for a diagnosis and proper treatment.

Causes

The cause of rosacea is unknown, but it could be due to an overactive immune system, heredity, environmental factors or a combination of these. Rosacea is not caused by poor hygiene and it's not contagious.

Flare-ups might be triggered by:

• Hot drinks and spicy foods

• Red wine and other alcoholic beverages

• Temperature extremes

• Sun or wind

• Emotions

• Exercise

• Drugs that dilate blood vessels, including some blood pressure medications

• Some cosmetic, skin or hair care products

Risk factors

Anyone can develop rosacea. But you may be more likely to develop it if you:

• Are female

• Have skin that burns easily in the sun

• Are over age 30

• Smoke

• Have a family history of rosacea

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Delgocitinib safe, efficacious in chronic hand eczema

Delgocitinib safe, efficacious in chronic hand eczema
Key takeaways:
• 49.2% of patients with chronic hand eczema experienced a 75% improvement with 16 weeks of treatment with delgocitinib.
• 74.4% of patients in the treatment group had a 4-point improvement in DLQI.
NEW ORLEANS — Phase 3 trial results found delgocitinib cream to significantly improve patient and clinician-reported outcomes of hand eczema, according to a presenter at the American Academy of Dermatology Annual Meeting.
“Chronic hand eczema is one of the most frequent and chronic inflammatory disorders affecting hands,” Robert Bissonnette, MD, MSc, CEO and medical director of Innovaderm, said during his presentation.
Current chronic hand eczema (CHE) treatments often have unsatisfactory results, Bissonnette continued.
The phase 3 DELTA 1 trial included 487 adult patients with severe chronic hand eczema randomly assigned 2:1 to delgocitinib 20 mg/g cream or vehicle twice daily for 16 weeks. The primary endpoint was the proportion of patients reaching an IGA of clear or almost clear with a 2-grade difference from baseline; however, the scale for almost clear was different than in previous studies, according to Bissonnette.
“In order to be almost clear, the only sign that could be present on the skin was barely perceptible erythema,” he said.
At week 16, 19.7% of those in the treatment group reached this endpoint, compared with 9.9% of those in the vehicle group.
“When I look at this and I look at patients who have concluded this trial, I see a disconnect. I think this is not really representative of the efficacy of the drug,” Bissonnette said. “This is my personal opinion, but I think the reason why this is the case is because of the IGA scale that was used.”
The proportion of patients who met the secondary endpoint of a 75% and 90% improvement in Hand Eczema Severity Index (HECSI) and 4-point improvement in DLQI from baseline were 49.2%, 29.5% and 74.4% in the treatment group, respectively, compared with 23.5%, 12.3% and 50% in the vehicle group.
The most frequent adverse events were similar proportions between the study and vehicle group, and no major adverse cardia events were reported.
“Delgocitinib 20 mg/g provided significant improvement both in clinician assessment and DLQI and was well tolerated over a period of 16 weeks,” Bissonnette said.

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Shingles linked with higher risk for heart disease and stroke

 Research we’re watching

People who’ve had shingles have a higher long-term risk of developing a major cardiovascular problem, a large new analysis suggests.
The Harvard-led study, published online Nov. 16, 2022, by the Journal of the American Heart Association, tracked more than 200,000 American adults — none of whom had ever had a stroke or coronary artery disease — for up to 16 years. Using questionnaires, researchers collected information on shingles, stroke, and heart disease among participants every two years, confirming any diagnoses with medical records. Those who’d had shingles (a reactivation of the same virus that causes chickenpox) had a higher risk of a stroke or coronary artery disease compared with participants who had not had shingles. The elevated risk for stroke persisted for 12 years or longer after the shingles episode.
Much of the study’s data was collected before shingles vaccines became widely available. But even after that point, many people eligible for the vaccine — who include adults 50 and older — do not receive it, study authors said. They recommended getting vaccinated against shingles to lower the chances of developing not just the painful rash, but also the possible long-term cardiovascular effects.

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