Exercise
Wednesday, 29 March 2023
10 Natural Remedies to Relieve Allergies
Saturday, 25 March 2023
How to recognise early signs and symptoms of skin cancer
How to recognise early signs and symptoms of skin cancer
Thursday, 23 March 2023
Rosacea
Rosacea (roe-ZAY-she-uh) is a common skin condition that causes blushing or flushing and visible blood vessels in your face. It may also produce small, pus-filled bumps. These signs and symptoms may flare up for weeks to months and then go away for a while. Rosacea can be mistaken for acne, other skin problems or natural ruddiness.
Monday, 20 March 2023
Delgocitinib safe, efficacious in chronic hand eczema
Key takeaways:
• 49.2% of patients with chronic hand eczema experienced a 75% improvement with 16 weeks of treatment with delgocitinib.
• 74.4% of patients in the treatment group had a 4-point improvement in DLQI.
NEW ORLEANS — Phase 3 trial results found delgocitinib cream to significantly improve patient and clinician-reported outcomes of hand eczema, according to a presenter at the American Academy of Dermatology Annual Meeting.
“Chronic hand eczema is one of the most frequent and chronic inflammatory disorders affecting hands,” Robert Bissonnette, MD, MSc, CEO and medical director of Innovaderm, said during his presentation.
Current chronic hand eczema (CHE) treatments often have unsatisfactory results, Bissonnette continued.
The phase 3 DELTA 1 trial included 487 adult patients with severe chronic hand eczema randomly assigned 2:1 to delgocitinib 20 mg/g cream or vehicle twice daily for 16 weeks. The primary endpoint was the proportion of patients reaching an IGA of clear or almost clear with a 2-grade difference from baseline; however, the scale for almost clear was different than in previous studies, according to Bissonnette.
“In order to be almost clear, the only sign that could be present on the skin was barely perceptible erythema,” he said.
At week 16, 19.7% of those in the treatment group reached this endpoint, compared with 9.9% of those in the vehicle group.
“When I look at this and I look at patients who have concluded this trial, I see a disconnect. I think this is not really representative of the efficacy of the drug,” Bissonnette said. “This is my personal opinion, but I think the reason why this is the case is because of the IGA scale that was used.”
The proportion of patients who met the secondary endpoint of a 75% and 90% improvement in Hand Eczema Severity Index (HECSI) and 4-point improvement in DLQI from baseline were 49.2%, 29.5% and 74.4% in the treatment group, respectively, compared with 23.5%, 12.3% and 50% in the vehicle group.
The most frequent adverse events were similar proportions between the study and vehicle group, and no major adverse cardia events were reported.
“Delgocitinib 20 mg/g provided significant improvement both in clinician assessment and DLQI and was well tolerated over a period of 16 weeks,” Bissonnette said.

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Thursday, 16 March 2023
Shingles linked with higher risk for heart disease and stroke
The Harvard-led study, published online Nov. 16, 2022, by the Journal of the American Heart Association, tracked more than 200,000 American adults — none of whom had ever had a stroke or coronary artery disease — for up to 16 years. Using questionnaires, researchers collected information on shingles, stroke, and heart disease among participants every two years, confirming any diagnoses with medical records. Those who’d had shingles (a reactivation of the same virus that causes chickenpox) had a higher risk of a stroke or coronary artery disease compared with participants who had not had shingles. The elevated risk for stroke persisted for 12 years or longer after the shingles episode.
Much of the study’s data was collected before shingles vaccines became widely available. But even after that point, many people eligible for the vaccine — who include adults 50 and older — do not receive it, study authors said. They recommended getting vaccinated against shingles to lower the chances of developing not just the painful rash, but also the possible long-term cardiovascular effects.
Tuesday, 14 March 2023
Eczema Treatment
What is the Main Cause of Eczema?
Different stages and types of eczema affect so many people on a daily basis. The most common type of eczema is called atopic dermatitis which directly correlates with an inflammation of the skin. While its main cause is unknown, the condition appears to be an abnormal response of the body’s immune system. According to Medical News Today, a combination of genetic and environmental factors come into play when discussing the onset of eczema. 1 On the genetic side, if both parents have experienced an atopic skin condition before, the risk of the child developing eczema increases. Dairy products, soy products, and eggs can actually cause eczema flare-ups. A very common environmental factor that can bring out eczema symptoms includes direct contact with irritants such as soaps, detergents, and shampoos. If you or your child is allergic to allergens such as dust and pollen, this can also be a direct cause of eczema.
Now that you understand why eczema may have formed in the first place, it’s to time treat this skin condition. It’s very important to find an eczema dermatologist who you trust and feel comfortable with. This medical professional will be able to properly assess the symptoms and determine the best route to take for treatment.
There is no cure for eczema, however eczema treatment can heal the affected skin in order to prevent future flare-ups. At DCSI, we base treatment off of the patient’s age, the symptoms that are present, and any other medical conditions that can directly impact the recommended treatment. You can alleviate the symptoms by applying a topical cream or ointment administered by a dermatologist. There are even certain moisturizers that will help bring down the inflammation and you should consult with your doctor about the creams that will work best for your skin.
Controlling eczema and the symptoms that come with it is possible. If you are worried about red patches on the skin, it’s time to contact a dermatologist. Dermatology & Cutaneous Surgery Institute has offices in Delray Beach and Wellington that can help all patients treat any skin condition that is present. If you are in need of eczema treatment for kids or even for yourself, schedule an appointment with us today! We are happy to help everyone maintain healthy skin.
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